We are running 200 Linux PCs distributed all around the university (number constantly growing!), a Linux computer cluster, two student pools and several servers with Debian woody. Apart from the servers, all computers are integrated in the NIS+ domain and get their home-directories via NFS from a central SUN E450. They get updated via apt-get whereby all packages are adapted to the local circumstances beforehand, so that the users in the faculties do not have to do any system administration. The most important data of the clients are stored in a central MySQL database, which is connected during the installation and everyday administrative processes.
Debian was mainly chosen for its ease of administration and software updates. Its well-tested release policy reduces the amount of updates and guarantees stability. Furthermore lots of free documentation is available which allows insights into the technical details of the system.